In a Pathfinder game, we attributed a description of rumbling and rocks falling to the structure crumbling, due to us dispatching what we reasoned had been a
Load-Bearing Boss; in fact, the fallen foe was simply going
One-Winged Angel on us. We ran from the not-actually-crumbling structure, in what we thought was a clean getaway in an Indy Jones-esque action sequence...and missed the last chance to slay an evil dracolich-god before it was reborn on the material plane. Basically, we *LOST* the campaign at the last possible second. In retrospect, all the filthy dungeons, blood-engorged abominations, rotting diseases and Faustian deals up until that point really should have told us this final fight was going to be a tad darker.